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21/05/2020 Guidelines
EASA-ECDC COVID-19 Operational guidelines for management of passengers final

EASA (EUROPEAN UNION AVIATION SAFETY AGENCY)

Authors:
EASA (EUROPEAN UNION AVIATION SAFETY AGENCY)

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18/05/2020 Viewpoint
Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)...

Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) An Unprecedented Partnership for Unprecedented Times

JAMA

Authors:
Francis S. Collins, Paul Stoffels

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15/05/2020 Scientific Brief
Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19

WORLD HEALTH ORGANIZATION

Authors:
WORLD HEALTH ORGANIZATION

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08/05/2020 Open
Guidance for the management of adult patients with coronavirus disease 2019

Chinese Medical Journal

Authors:
Jie-Ming Qu, Chen Wang, Bin Cao

ABSTRACT

In December 2019, a novel coronavirus was identified in Wuhan City, Hubei Province, China and later the disease was named coronavirus disease 2019 (COVID-19). On March 11, 2020, the World Health Organization (WHO) officially announced that COVID-19 had reached global pandemic status. This article summarized the understanding of the etiology, pathogenesis, epidemiology, clinical characteristics, diagnosis, treatment, rehabilitation, and prevention and control measures of COVID-19 based on the available data and anti-epidemic experience in China.

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08/05/2020 Articles
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing

Science

Authors:
Luca Ferretti, Chris Wymant, Michelle Kendall, Lele Zhao, Anel Nurtay, Lucie Abeler-Dörner, Michael Parker, David Bonsall, Christophe Fraser

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27/04/2020 Editorial
Global regulatory agility during covid-19 and other health emergencies

BMJ

Authors:
Tippi K Mak, John CW Lim, Prapassorn Thanaphollert, Gugu N Mahlangu, Emer Cook, Murray M Lumpkin

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27/04/2020 Perspectives
Twentieth-Century Lessons for a Modern Coronavirus Pandemic

JAMA

Authors:
Angel Desai

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24/04/2020 Overview
Availability of medicines during COVID-19 pandemic

EUROPEAN MEDICINE AGENCY

Authors:
JAN JACOBS

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23/04/2020 Review
Recommendations for general surgery activities in a pandemic scenario (SARS-CoV-2)

BJS SOCIETY

Authors:
F. Di Marzo, M. Sartelli, R. Cennamo, G. Toccafondi, F. Coccolini, G. La Torre, G. Tulli, M. Lombardi, M. Cardi

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22/04/2020 Articles
COVID-19 Rapid Diagnostic Tests: use in low resource settings

INSTITUTE OF TROPICAL MEDICINE ANTWERP

Authors:
JAN JACOBS

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20 /04/2020 Guidelines
Managing COVID-19 symptoms (including at the end of life) in the community...

Managing COVID-19 symptoms (including at the end of life) in the community: summary of NICE guidelines

THE BMJ

Authors:
National Institute for Health and Care Excellence (NICE) in collaboration with NHS England and NHS Improvement

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09/04/2020 Editorial
Covid-19: should the public wear face masks?

THE BMJ

Authors:
Babak Javid, Michael P Weekes, Nicholas J Matheson

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09/04/2020 Articles
Interim Guidance for Basic and Advanced Life Support in Adults, Children...

Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With the Guidelines®-Resuscitation

CIRCULATION

Authors:
Dana P. Edelson, Comilla Sasson , Paul S. Chan, Dianne L. Atkins, Khalid Aziz, Lance B. Becker, Robert A. Berg, Steven M. Bradley, Steven C. Brooks, Adam Cheng, Marilyn Escobedo, Gustavo E. Flores, Saket Girotra, Antony Hsu, Beena D. Kamath-Rayne, Henry C. Lee, Rebecca E. Lehotzky, Mary E. Mancini, Raina M. Merchant, Vinay M. Nadkarni, Ashish R. Panchal, Mary Ann R. Peberdy, Tia T. Raymond, Brian Walsh, David S. Wang, Carolyn M. Zelop, Alexis Topjian



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09/04/2020 Analysis
Face masks for the public during the covid-19 crisis

THE BMJ

Authors:
Trisha Greenhalgh, Manuel B Schmid, Thomas Czypionka, Dirk Bassler, Laurence Gruer

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07/04/2020 News
Covid-19: What is the evidence for cloth masks?

THE BMJ

Authors:
Elisabeth Mahase

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06/04/2020 Circolare
Circolare sulle procedure semplificate per gli studi e gli usi compassionevoli...

Circolare sulle procedure semplificate per gli studi e gli usi compassionevoli per l’emergenza da covid-19

AIFA

Authors:
AIFA

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30 /03/2020Guidelines
Coping with stress during the 2019-nCoV outbreak

World Health Organization

 

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27/03/2020 Guidelines
Consensus guidelines for managing the airway in patients with COVID-19

WILEY ONLINE LIBRARY

Authors:
T. M. Cook K. El‐Boghdadly B. McGuire A. F. McNarry A. Patel A. Higgs

ABSTRACT

Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious. Airway management of patients with COVID-19 is high risk to staff and patients. We aimed to develop principles for airway management of patients with COVID-19 to encourage safe, accurate and swift performance. This consensus statement has been brought together at short notice to advise on airway management for patients with COVID-19, drawing on published literature and immediately available information from clinicians and experts. Recommendations on the prevention of contamination of healthcare workers, the choice of staff involved in airway management, the training required and the selection of equipment are discussed. The fundamental principles of airway management in these settings are described for: emergency tracheal intubation; predicted or unexpected difficult tracheal intubation; cardiac arrest; anaesthetic care; and tracheal extubation. We provide figures to support clinicians in safe airway management of patients with COVID-19. The advice in this document is designed to be adapted in line with local workplace policies.

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25/03/2020 Report
COVID-19: An executive report

ACCADEMIA DEI LINCEI

Authors:
Maurizio Cecconi, Guido Forni, Alberto Mantovani

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23/03/2020 Link
Coronavirus COVID-19 (SARS-CoV-2)

Johns Hopkins Medicine

Authors:
Paul G. Auwaerter

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19/03/2020 Press Release
Call to pool research resources into large multi-centre, multi-arm clinical trials to generate sound evidence on COVID-19 treatments

European Medicines Agency Science Medicine Health

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15/03/2016 Articles
Impact analysis studies of clinical prediction rules relevant to primarycare...

Impact analysis studies of clinical prediction rules relevant to primarycare: a systematic review

BMJ

Authors:
Emma Wallace, Maike J M Uijen, Barbara Clyne, Atieh Zarabzadeh, Claire Keogh
ABSTRACT
Objectives Following appropriate validation, clinical prediction rules (CPRs) should undergo impact analysis to evaluate their effect on patient care. The aim of this systematic review is to narratively review and critically appraise CPR impact analysis studies relevant to primary care. Setting Primary care. Participants Adults and children. Intervention Studies that implemented the CPR compared to usual care were included. Study design Randomised controlled trial (RCT), controlled before–after, and interrupted time series. Primary outcome Physician behaviour and/or patient outcomes. Results A total of 18 studies, incorporating 14 unique CPRs, were included. The main study design was RCT (n=13). Overall, 10 studies reported an improvement in primary outcome with CPR implementation. Of 6 musculoskeletal studies, 5 were effective in altering targeted physician behaviour in ordering imaging for patients presenting with ankle, knee and neck musculoskeletal injuries. Of 6 cardiovascular studies, 4 implemented cardiovascular risk scores, and 3 reported no impact on physician behaviour outcomes, such as prescribing and referral, or patient outcomes, such as reduction in serum lipid levels. 2 studies examined CPRs in decision-making for patients presenting with chest pain and reduced inappropriate admissions. Of 5 respiratory studies, 2 were effective in reducing antibiotic prescribing for sore throat following CPR implementation. Overall, study methodological quality was often unclear due to incomplete reporting. Conclusions Despite increasing interest in developing and validating CPRs relevant to primary care, relatively few have gone through impact analysis. To date, research has focused on a small number of CPRs across few clinical domains only

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12/03/2020 Articles
Managing the Respiratory care of patients with COVID-19

ITS (ITALIAN THORACIC SOCIETY)

Authors:
Harari Sergio Alfonso, Vitacca Michele, Blasi Francesco, Centanni Stefano, Santus Pier Achille, Tarsia Paolo

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10 /03/2020 Technical Report
Novel coronavirus (SARS-CoV-2) Discharge criteria for confirmed COVID-19 cases...

Novel coronavirus (SARS-CoV-2). Discharge criteria for confirmed COVID-19 cases – When is it safe to discharge COVID-19 cases from the hospital or end home isolation?

ECDC

Authors:
ECDC



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02/03/2020 Interim guidance
Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases

WORLD HEALTH ORGANIZATION

Authors:
WORLD HEALTH ORGANIZATION

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18/02/2020 Guidelines
Surface sampling of coronavirus disease (COVID-19): A practical “how to” protocol for health care and public health professionals

World Health Organization

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10 /02/2020 Guidelines
Guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV

ECDC TECHNICAL REPORT

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05/02/2020 Guidelines
Risk Assessment of Novel Coronavirus COVID-19 Outbreaks Outside China

MDPI - Journal of Clinical Medicine

Authors:
Péter Boldog, Tamás Tekeli, Zsolt Vizi, Attila Dénes, Ferenc A. Bartha and Gergely Röst

Abstract:

We developed a computational tool to assess the risks of novel coronavirus outbreaks outside of China. We estimate the dependence of the risk of a major outbreak in a country from imported cases on key parameters such as: (i) the evolution of the cumulative number of cases in mainland China outside the closed areas; (ii) the connectivity of the destination country with China, including baseline travel frequencies, the effect of travel restrictions, and the efficacy of entry screening at destination; and (iii) the efficacy of control measures in the destination country (expressed by the local reproduction number Rloc). We found that in countries with low connectivity to China but with relatively high Rloc, the most beneficial control measure to reduce the risk of outbreaks is a further reduction in their importation number either by entry screening or travel restrictions. Countries with high connectivity but low Rloc benefit the most from policies that further reduce Rloc. Countries in the middle should consider a combination of such policies. Risk assessments were illustrated for selected groups of countries from America, Asia, and Europe. We investigated how their risks depend on those parameters, and how the risk is increasing in time as the number of cases in China is growing.

Keywords:
novel coronavirus; transmission; risk assessment; interventions; travel; outbreak; COVID-19; compartmental model; branching process

Target audience
Public health authorities in the EU/EEA Member States (MS) and the UK.

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03/02/2020 Guidelines
COVID-19 rapid guideline: managing symptoms (including at the end of life) in the community

NICE guideline

Authors:
Péter Boldog, Tamás Tekeli, Zsolt Vizi, Attila Dénes, Ferenc A. Bartha and Gergely Röst

Abstract:

The purpose of this guideline is to provide recommendations for managing COVID‑19 symptoms for patients in the community, including at the end of life. It also includes recommendations about managing medicines for these patients, and protecting staff from infection. This guideline is for: health and care practitioners health and care staff involved in planning and delivering services commissioners The recommendations bring together existing national and international guidance and policies advice from specialists working in the NHS from across the UK. These include people with expertise and experience of treating patients for the specific health conditions covered by the guidance during the current COVID-19 pandemic.

Keywords:
novel coronavirus; transmission; risk assessment; interventions; travel; outbreak; COVID-19; compartmental model; branching process

Target audience
Public health authorities in the EU/EEA Member States (MS) and the UK.

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CORONAVIRUS LIBRARY

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