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Home>Events>The Eighteenth International Conference on Endothelin
Video & Slide

12 October 2023 - Day 1

  • Opening remarks:

    Speaker Carmine Cardillo

    Session date 12/10/2023 - 08:50

  • Recent advances in drugs acting on the endothelin system

    Speaker Anthony Davenport

    Session date 12/10/2023 - 09:00

  • Identification of new therapeutic vulnerabilities in cancer exploiting the molecular ET-averse

    Speaker Anna Bagnato

    Session date 12/10/2023 - 09:30

  • Discussion 1

    Speaker -

    Session date 12/10/2023 - 09:40

  • The intersection of the endothelin-1 receptor axis with mechanical cues affects PARP inhibitor response in highgrade serous ovarian cancer

    Speaker Giuliano Tocci

    Session date 12/10/2023 - 09:50

  • Discussion 2

    Speaker -

    Session date 12/10/2023 - 10:00

  • Regulation of invasion and peritoneal dissemination of serous ovarian cancer by Endothelin A receptor and Integrin ꞵ interplay

    Speaker I. Masi

    Session date 12/10/2023 - 10:15

  • Discussion 3

    Speaker -

    Session date 12/10/2023 - 10:30

  • Preclinical immunotherapeutic approaches to treat tumours overexpressing endothelin receptors

    Speaker D. Boquet

    Session date 12/10/2023 - 10:35

  • Discussion 4

    Speaker -

    Session date 12/10/2023 - 10:45

  • The endothelin-1/ miR-200b-c/ZEB1 circuit drives novel gasdermin E nuclear functions to fuel inflammatory responses and metastatic progression in high-grade serous ovarian

    Speaker R. Sestito

    Session date 12/10/2023 - 10:50

  • Discussion 5

    Speaker -

    Session date 12/10/2023 - 11:30

  • KeyNote Lecture: Non-selective endothelin receptor antagonism in resistant hypertension: the PRECISION trial

    Speaker Ernesto Schiffrin

    Session date 12/10/2023 - 11:40

  • Discussion 6

    Speaker -

    Session date 12/10/2023 - 11:50

  • Evidence for endothelin regulation of the suprachiasmatic nucleus – the master circadian clock

    Speaker David M. Pollock

    Session date 12/10/2023 - 12:00

  • Discussion 7

    Speaker -

    Session date 12/10/2023 - 12:15

  • Hypertension Worsens Endothelin-1-Mediated Vasoconstrictor Tone in Adults with Obesity

    Speaker Colin Berry

    Session date 12/10/2023 - 12:20

  • Discussion 8

    Speaker -

    Session date 12/10/2023 - 12:30

  • Environmental Enrichment after Ischemic Stroke Decreases Brain Endothelin -1 (ET-1) and ETA Receptor Expression in Spontaneously Hypertensive Rats

    Speaker Y. Abdul

    Session date 12/10/2023 - 12:35

  • Discussion 9

    Speaker -

    Session date 12/10/2023 - 12:45

  • KeyNote Lecture: Effects of endothelin on the brain microvasculature

    Speaker Adviye Ergul

    Session date 12/10/2023 - 15:15

  • Discussion 10

    Speaker -

    Session date 12/10/2023 - 15:30

  • Sovateltide, a neural progenitor cell therapeutic for the treatment of acute ischemic stroke, shows no effect on the thrombolytic activity of t-PA

    Speaker M. Lavhale

    Session date 12/10/2023 - 15:45

  • Discussion 11

    Speaker -

    Session date 12/10/2023 - 16:00

  • Role of Sovateltide Mediated Agonism of Endothelin B Receptors in Regeneration and Repair in the Adult Brain after Ischemic Stroke

    Speaker A. Ranjan

    Session date 12/10/2023 - 16:05

  • Discussion 12

    Speaker -

    Session date 12/10/2023 - 16:10

  • Intranasal inhibition of brain endothelin receptor A (ETA) exerts positive effects on cognitive functions in a hypoperfusion model of VCID in diabetic rats

    Speaker Y. Abdul

    Session date 12/10/2023 - 16:15

  • Discussion 13

    Speaker -

    Session date 12/10/2023 - 16:30

  • Invited Lecture: Advances in the treatment of neurologic disorders using drugs active on the endothelin system

    Speaker Anil Gulati

    Session date 12/10/2023 - 16:40

  • Discussion 14

    Speaker -

    Session date 12/10/2023 - 17:00

13 October 2023 - Day 2

  • Review of recent clinical trials with drugs targeting the endothelin system

    Speaker H. Lambers Heerspink

    Session date 13/10/2023 - 09:00

  • First-line treatment with sparsentan, a dual endothelin and angiotensin receptor antagonist, in patients with immunoglobulin A nephropathy: initial results of the SPARTAN study

    Speaker M. Sayer

    Session date 13/10/2023 - 09:30

  • Discussion 15

    Speaker -

    Session date 13/10/2023 - 09:40

  • Endothelium-derived endothelin-1 mediates sickle cell inflammation and nephropathy

    Speaker Jennifer Pollock

    Session date 13/10/2023 - 09:45

  • Discussion 16

    Speaker -

    Session date 13/10/2023 - 09:55

  • Endothelin A receptor antagonist promotes iron recycling in murine models of iron overload

    Speaker M. Kasztan

    Session date 13/10/2023 - 10:00

  • Discussion 17

    Speaker -

    Session date 13/10/2023 - 10:10

  • Invited Lecture: Is there a role of endothelin targeting for nephroprotection in the era of SGLT2 or mineralcorticoid receptor inhibition?

    Speaker Pierre-Louis Tharaux

    Session date 13/10/2023 - 10:15

  • Discussion 18

    Speaker -

    Session date 13/10/2023 - 10:40

  • KeyNote Lecture: Could targeting the endothelin system become a suitable approach in HFpEF?

    Speaker Kieran Docherty

    Session date 13/10/2023 - 11:05

  • Discussion 19

    Speaker -

    Session date 13/10/2023 - 11:15

  • Endothelin mediates communication between heart and skeletal muscle during heart failure

    Speaker S. Das

    Session date 13/10/2023 - 11:35

  • Discussion 20

    Speaker -

    Session date 13/10/2023 - 11:50

  • Endothelin-1 Impairs the Capacity of Brain Endothelial Cells to Release Tissue-Type Plasminogen Activator

    Speaker A. Berry

    Session date 13/10/2023 - 11:55

  • Discussion 21

    Speaker -

    Session date 13/10/2023 - 12:05

  • Dissecting endothelin-dependent functional responses in human cardiac organoids to identify new heart failure targets

    Speaker S. Foster

    Session date 13/10/2023 - 12:15

  • Endothelin in coronary artery diseases

    Speaker Matthias Barton

    Session date 13/10/2023 - 12:20

  • Discussion 22

    Speaker -

    Session date 13/10/2023 - 12:20

  • Invited Lecture: Endothelin in coronary artery diseases

    Speaker Matthias Barton

    Session date 13/10/2023 - 12:25

  • Hot Topic Presentation: Mandibulofacial dysostosis with alopecia resulting from ETAR gain-of-function

    Speaker Yukiko Kurihara

    Session date 13/10/2023 - 12:30

  • KeyNote Lecture: Role of endothelin in the oxidative stress associated with diabetic vasculopathy

    Speaker Rhian M Touyz

    Session date 13/10/2023 - 12:40

  • Discussion 23

    Speaker -

    Session date 13/10/2023 - 12:50

  • Poster Discussion

    Speaker Ivana Vanĕčková

    Session date 13/10/2023 - 14:00

  • Adipocyte specific ETB receptor knockout attenuates insulin resistance and dyslipidemia in mice fed high fat diet

    Speaker J. Speed

    Session date 13/10/2023 - 15:30

  • Discussion 24

    Speaker -

    Session date 13/10/2023 - 15:40

  • Loss of Endothelin-2 Impairs Early-Stage Adipocyte Differentiation

    Speaker P. Rinastiti

    Session date 13/10/2023 - 15:45

  • Discussion 25

    Speaker -

    Session date 13/10/2023 - 15:55

  • Endothelin-1 promotes perivascular adipose tissue dysfunction in obese mice via Nrf2 downregulation and oxidative stress

    Speaker Rita Tostes

    Session date 13/10/2023 - 16:00

  • Discussion 26

    Speaker -

    Session date 13/10/2023 - 16:10

  • Invited Lecture: Role of endothelin and endothelin antagonism in Non-alcoholic fatty liver disease

    Speaker Wilhelmus Kwanten

    Session date 13/10/2023 - 16:15

  • Discussion 27

    Speaker -

    Session date 13/10/2023 - 16:45

14 October 2023 - Day 3

  • KeyNote Lecture: Update on the use of endothelin antagonists in pulmonary hypertension

    Speaker Noriaki Emoto

    Session date 14/10/2023 - 09:00

  • Discussion 28

    Speaker -

    Session date 14/10/2023 - 09:25

  • Dapagliflozin and ambrisentan co-administration in patients hospitalised with COVID-19. A report from mulTi-Arm therapeutiC sTudy in pre-Icu patients admitted with Covid-19 – Experimental drugs and mechanisms (TACTIC-E)

    Speaker P. Ambery

    Session date 14/10/2023 - 09:30

  • Discussion 29

    Speaker -

    Session date 14/10/2023 - 09:40

  • Acute amelioration of inflammatory activity caused by endothelin-2 deficiency during acute lung injury

    Speaker A. Musthafa

    Session date 14/10/2023 - 09:45

  • Discussion 30

    Speaker -

    Session date 14/10/2023 - 09:55

  • Targeting endothelin signalling for combating SARS-CoV-2-induced osteochondral defect

    Speaker M. T. Au

    Session date 14/10/2023 - 10:00

  • Discussion 31

    Speaker -

    Session date 14/10/2023 - 10:10

  • Invited Lecture: Role of endothelin in vasculitis

    Speaker Neeraj Dhaun

    Session date 14/10/2023 - 10:15

  • Discussion 32

    Speaker -

    Session date 14/10/2023 - 10:45

  • KeyNote Lecture: Endothelin and hair follicle regeneration

    Speaker Michael Rendl

    Session date 14/10/2023 - 11:05

  • Discussion 33

    Speaker -

    Session date 14/10/2023 - 11:30

  • Serum endothelin-1 increased in Indonesian hypertensive females: the result of Sleman HDSS populational survey

    Speaker A. B. Hartopo

    Session date 14/10/2023 - 11:35

  • Discussion 34

    Speaker -

    Session date 14/10/2023 - 11:40

  • Leptin is a novel upregulator of placental endothelin-1 in preeclampsia

    Speaker J. Faulkner

    Session date 14/10/2023 - 11:50

  • Discussion 35

    Speaker Massimo Cardillo

    Session date 14/10/2023 - 12:00

  • Sex-specific role for the clock protein PER1 in the regulation of renal ET-1 in salt-sensitive hypertension

    Speaker Michelle Gumz

    Session date 14/10/2023 - 12:05

  • Discussion 36

    Speaker -

    Session date 14/10/2023 - 12:15

  • Role of endothelin in pre-eclampsia

    Speaker Jan Danser

    Session date 14/10/2023 - 12:20

  • Discussion 37

    Speaker -

    Session date 14/10/2023 - 12:50

  • Highlights of the Meeting

    Speaker Masashi Yanagisawa

    Session date 14/10/2023 - 15:15

  • Closing remarks of the Conference Chairs

    Speaker Carmine Cardillo

    Session date 14/10/2023 - 15:45

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